Spinal muscular atrophy (SMA) is a genetic neurodegenerative disease that affects motor neurons in the spinal cord, leading to progressive muscle weakness and atrophy. SMA is caused by mutations in the SMN1 gene, which encodes the SMN protein, which is essential for the survival and function of motor neurons. Traditional https://stemplus.clinic/disease-treatment/sma/ treatments for SMA focus on managing symptoms and improving patients' quality of life, including physical therapy, respiratory support, and nutrition. However, these treatments do not address the underlying cause of SMA and cannot stop the progression of the disease. In recent years, stem cells have been the subject of active research as a potentially new approach to treating SMA, aimed at replacing lost motor neurons and improving muscle function.